Most of the brain is influenced by the acetycholinergenic receptor system, divided into two types: nicotinic acetylcholinergenic and muscarinic acetylcholinergenic. Acetylcholine and either nicotine or muscarine (respectively) can activate these receptors, giving you success in moving, staying still, or thinking. Acetylcholine is sourced both endogenously (made by your body) and exogenously (combined from acetic acid and choline in your diet). Nicotine is only, and very commonly, sourced from your diet (Solanaceous veggies, etc.). Muscarine is only availably from certain mushrooms and is not common in diet (so these receptors typically operate with only acetylcholine).
The diagram below illustrates that nicotine activates over half of your brain, and also your substantia nigra (for dopamine) and your locus coeruleus (for adrenaline).
Source:
https://www.cnsforum.com/educationalresources/imagebank/dementia_cholinergic/rcpt_sys_ach_dist
No comments:
Post a Comment